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I would also keep these in mind:
There is a performance hit when dedup is enabled, so that should be kept in mind as well.
Workloads that might benefit from deduplication, but aren't always good candidates for deduplication. For example, the following workloads could work well with deduplication, but you should evaluate the benefits of deduplication first:
- General purpose Hyper-V hosts
- SQL servers
- Line-of-business (LOB) servers
https://docs.microsoft.com/en-us/windows-server/storage/data-deduplication/interop
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