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The only region in South America is São Paulo https://docs.aws.amazon.com/AWSEC2/latest/UserGuide/using-regions-availability-zones.html
The edge is selected automatically for you from the location of the requester, but you cannot select on which edge your assets are deployed, they are deployed in every edge location and served to the client from the closest/faster location.
But because you are talking about deploying a server, you can do this only on an AWS region, and in your cause it's São Paulo
If instead you talk about Cloudfront functions, your function is deployed in every edge automatically, so you don't need to decide which edge to use https://aws.amazon.com/blogs/aws/introducing-cloudfront-functions-run-your-code-at-the-edge-with-low-latency-at-any-scale/
You should also test latency from the US regions. I don't know the layout of the interconnections to Guatemala, but at one time, it was lower latency to use US Regions from the south pacific than to use Singapore, which was geographically closer because the route to Singapore was through the US.