After 4 days of these intermittent connectivity issues, the issue suddenly stopped with no action on our part other than making a post here. I'm assuming AWS monitors these posts and intervenes behind the scenes on issues like this, and that is what got our issue resolved.
I only wish there would have been some sort of confirmation or feedback to us if that's what occurred.
This could be a DNS issue (lookup is failing) or some other network problem. Given that this is an intermittent problem the best thing to do is to raise a support case and have the team troubleshoot this with you.
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