Best region to chose for AWS API Gateway in Israel

Hi, this page may help you: https://aws.amazon.com/about-aws/global-infrastructure/regions_az/

Select Middle East tab to see what's available: Tel Aviv is an edge location currently

If you want to choose a region for Israeli customers, we did announce a region in Israel that should be live this year. In the meanwhile, use of the Europe regions like Dublin or Frankfurt. To improve the performance, use an Edge Optimized API, which will use a CloudFront distribution.