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You're describing the security group attached to the destination instance, but what's configured in the security group of the source instance? Would you be comfortable sharing screenshots of a) the security groups attached to the ENI of the source instance, b) the SGs attached to the ENI of the destination instance, c) the outbound rules in the security group(s) of the source instance, and d) the inbound rules of the SG(s) of the destination instance?
The symptoms you're describing would match if both the instances were using the same SG, i.e., "a" and "b" would be the same.
You can also use the VPC Reachability Analyzer in the console to see a visualisation of the path your traffic is taking and how all the specific parts of your configuration, such as security groups, interact to cause the connection to work or not to work end to end: https://docs.aws.amazon.com/vpc/latest/reachability/what-is-reachability-analyzer.html
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