What do we need to configure to enable a multi availability zone Simple Email Service configuration?

Hello,

Thank you for contacting AWS.

Currently there is no feature to automatically failover between AWS regions in SES. SES does however, have resiliency in a single region due to the AWS global infrastructure being built around AWS Regions and Availability Zones. AWS Availability Zones are highly available and more fault tolerant and scalable than traditional single, or multiple, data centre infrastructures [1].

That being said, you can use same configurations in multiple regions so that you can use multiple regions to send emails.

• You can verify a domain ( for example example.com) in multiple regions by adding the CNAME records for each region in domain's DNS provider.
  [+] Verify domain : https://docs.aws.amazon.com/ses/latest/dg/creating-identities.html

• If you want to send emails to non-verified addresses, then you can request to move your account out of Sandbox by filling the form given here : https://docs.aws.amazon.com/ses/latest/dg/request-production-access.html

• You can then start to send emails from the respective region by following any of the method given here : https://docs.aws.amazon.com/ses/latest/dg/send-email.html.
  Note that each SES region will have it's own endpoint so you will need to change the endpoint in your application. To see the list of SES API and SMTP endpoints, please refer[2].

Also, if you are using the SMTP interface, then you will need to use the region specific credentials. SMTP credentials are unique to the region they were created in, so it is not possible to use the same credentials in different regions.
[+] SMTP credentials : https://docs.aws.amazon.com/ses/latest/dg/smtp-credentials.html

Please feel free to reach out for further queries or concerns.

References:
[1] https://docs.aws.amazon.com/ses/latest/dg/disaster-recovery-resiliency.html
[2] https://docs.aws.amazon.com/general/latest/gr/ses.html#ses_region