It is possible to interact with Lightsail Bucket using S3Client?

In the case of a Lightsail bucket, uploading was not possible unless an access key and secret access key were issued. So, please follow the steps described in the document below to issue an access key, set it in your code, and run it. I ran the code below with Lambda and was able to upload the file to a Lightsail bucket. https://docs.aws.amazon.com/lightsail/latest/userguide/amazon-lightsail-creating-bucket-access-keys.html

import { PutObjectCommand, S3Client } from "@aws-sdk/client-s3";

const client = new S3Client({
    credentials: {
    accessKeyId: "AccessKey",
    secretAccessKey: "SecretAccessKey",
  }});

export const handler = async (event) => {
  const command = new PutObjectCommand({
    Bucket: "bucket-name",
    Key: "hello-s3.txt",
    Body: "Hello S3!",
  });

  try {
    const response = await client.send(command);
    console.log(response);
    return {
      statusCode: 200,
      body: JSON.stringify(response),
    };
  } catch (err) {
    console.error(err);
    return {
      statusCode: 500,
      body: JSON.stringify(err),
    };
  }
};