Can AWS Fault injection simulator used for AZ failure simulation?

As of today, AWS Fault Injection Simulator does not support complete Availability Zone failure or API Gateway failure.

These feature requests have been passed to the FIS team and will be reviewed.

AZ failures are much more complicated than they seem on the surface. AWS Fault Injection Simulator can be used to simulate outages that affect your infrastructure in ways that are similar to the way a real AZ outage might. However, this requires a clear understanding of how the control plane and data plane for your service will react to a failure. See this blog post and this workshop for some additional details.

Per an October 2022 blog post - https://aws.amazon.com/about-aws/whats-new/2022/10/aws-fault-injection-simulator-network-connectivity-disruption/

AWS Fault Injection Simulator (FIS) now supports network connectivity disruption as a new FIS action type. Using the new disrupt connectivity action in AWS FIS, you can inject a variety of connectivity issues as part of an AWS FIS experiment. Supported connectivity issues include disrupting all traffic, or, limiting the disruption to traffic to/from a specific Availability Zone, VPC, custom prefix list, or service (including Amazon S3 and DynamoDB)

Documentation - https://docs.aws.amazon.com/fis/latest/userguide/fis-actions-reference.html#network-actions-reference