Cross-Region CDK Deployments without bootstrapping every region

Is it possible to deploy the same stack across multiple regions in the same account or different accounts without actually bootstrapping every region in every account, rather use the same bootstrapped IAM Roles created in a single region.

I understand certain resources such as the KMS Key, SSM Parameter Store are region bound, however resources which are global such as IAM Roles and S3 Buckets don't need to be recreated for every region.

Please advise if this is possible with customized bootstrapping? If so, how to exactly tweak the bootstrap template for this?