AppStream Latency Issue

I have a district that we have deployed Adobe Creative Cloud on AppStream (stream.graphics-design.xlarge instances). In a room of 20 students using Chromebooks, some students are just fine, and when they are typing, the application is responsive, and for a few students, when typing, there is a delay when they type before characters show up. If you go into the AppStream client and check the latency on these devices, it is only 46ms. The school district has a 1Gbps fiber connection, and their overall bandwidth usage is 40% - 50%, so I don't think their uplink is the issue. Any other thoughts or things to look at to troubleshoot the issue?