Connection refused problems of my EC2 instance

Hi, are you exposing the appropriate ports on the dockerfile?

Are you able to ssh into this machine? Is this machine on a public subnet or a private subnet? If it is on a public subnet then you should be able to connect as per the security group settings. One more thing to check would be if you have any NACLs on the subnet preventing inbound access on these ports.

You may also want to look at this Premium Support Knowledge Center article to see if you can find any pointers - https://aws.amazon.com/premiumsupport/knowledge-center/ec2-linux-resolve-ssh-connection-errors/

Also look at the docker logs to see if you can find anything there.